Allo Chassis™: Immune-cloaked iPSC cell lines for cost-effective, fast development.

Cellistic’s Allo Chassis™ offers immune-cloaked iPSC cell lines derived from primary CD34 or CD4+ T-cells, ready for immediate use. These readily-available cell lines are reprogrammed and edited using Cellistic IP and extensively documented by following GMP principles, saving valuable time and development costs, and ensuring a compliant start to your cell therapy development.

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Why choose Allo Chassis™?

Allo Chassis™ is ideal for innovators pursuing ready-made HLA-null iPSCs cell lines for the development of allogeneic cell therapies. Cellistic cell lines manufactured under GMP principles and using proprietary IP allow for a broad range of applications – in regenerative medicine, immune-evasive CAR-T and NK cell therapies, tissue engineering and organ transplantation – with the certainty that the product is compliant all the way to commercialization.

GMP-ready
Manufactured based on cGMP principles in Cellistic's state-of-the-art, EMA-approved facility.

Fast-track development
Save the time sourcing primary cells, reprograming and editing by directly using our immune-cloaked cell lines.

Clear cost structure
Costs and license fees are defined through commercialization.

Leverage iPSC know-how and IP
Our Allo Chassis™ is created by a team that has developed numerous iPSC cell lines and edited using our proprietary STAR-CRISPR™ technology.

What you get with Allo Chassis™.

When you put Allo Chassis™ to work, you get a complete solution designed to minimize complexity and maximize value. And you get it delivered by an experienced, multidisciplinary team housed in Europe’s first facility exclusively dedicated to iPSC-based allogeneic cell therapy manufacturing.

Ready-to-use iPSC cell lines

High-quality, immune-cloaked lines available for immediate use and customization.

IP licensing

Clear, flexible licensing for commercialization of Allo Chassis™ technology.

GMP documentation

Comprehensive documentation to support your IND application process.

Differentiation capabilities

Summary of the differentiation capabilities of the customer Allo Chassis™ cell lines.

Support for gene editing & development

Tailor cell lines to meet the needs of your specific therapy.

Discover how Allo Chassis™ can support your allogeneic cell therapy development.

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How is it made?
The science behind Allo Chassis™.

Allo Chassis™ is powered by advanced gene-editing technologies and automation, ensuring high-quality, scalable solutions for your cell therapy development.

Immune cloaking

Expertly engineered strategies to minimize immune recognition and enhance compatibility.

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Cell line development automation

Built using automated processes, Allo Chassis™ integrates scalable workflows that deliver consistent, reliable results.

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STAR-CRISPR™ technology

Our STAR-CRISPR™ gene-editing technology ensures precision and reproducibility, with strong IP protection and clear licensing terms.

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Quality control strategy

We implement rigorous quality assurance processes at every stage, ensuring consistent, precise results that meet the highest standards. Our commitment to accuracy and reliability means you can trust our work to deliver dependable outcomes every time.

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GMP considerations for iPSC cell lines

Allo Chassis™ is developed following current Good Manufacturing Practice (cGMP) standards, with rigorous quality control and validation for optimal cell line quality and low passage numbers.

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