In this webinar, we review current approaches for executing complex genome edits at high precision and efficiency, alongside the quality, safety, and regulatory considerations that guide iPSC genome engineering programs for next-generation cell therapies.
Highlights of the webinar:
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How nuclease architecture influences editing precision, off-target risk, and manufacturability
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Comparative data on the performance of different CRISPR systems
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Use of bioinformatic tools to design, predict, and evaluate genome edits
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Allo Chassis™ case study applying the STAR-CRISPR™ gRNA workflow to create HLA Class I & II null iPSC lines via B2M and CIITA knockout
